ethyl 3-oxo-4-phenoxybutanoate

ethyl 3-oxo-4-phenoxybutanoate - Names and Identifiers

Name	Ethyl 3-oxo-4-phenoxybutyrate
Synonyms	Ethyl 4-phenoxyacetoacetate Ethyl 3-oxo-4-phenoxybutyrate ethyl 3-oxo-4-phenoxybutyrate ethyl 3-oxo-4-phenoxybutanoate 3-Oxo-4-phenoxybutanoic acid ethyl ester Butanoic acid, 3-oxo-4-phenoxy-, ethyl ester
CAS	41051-18-7
EINECS	2551894
InChI	InChI=1/C12H14O4/c1-2-15-12(14)8-10(13)9-16-11-6-4-3-5-7-11/h3-7H,2,8-9H2,1H3

ethyl 3-oxo-4-phenoxybutanoate - Physico-chemical Properties

Molecular Formula	C12H14O4
Molar Mass	222.24
Density	1.130±0.06 g/cm3(Predicted)
Boling Point	105-110 °C(Press: 0.1 Torr)
Flash Point	136.7°C
Vapor Presure	0.000445mmHg at 25°C
pKa	9.92±0.46(Predicted)
Refractive Index	1.5

ethyl 3-oxo-4-phenoxybutanoate - Introduction

Ethyl 3-oxo-4-phenoxybutyrate is an organic compound with the chemical formula C12H14O4. The following is a description of its nature, use, preparation and safety information:

Nature:
Ethyl 3-oxo-4-phenoxybutyrate is a colorless to light yellow liquid with a special fragrance. It has a density of about 1.2 g/mL and a boiling point of 245-250°C.

Use:
Ethyl 3-oxo-4-phenoxybutyrate is an important organic synthesis intermediate, which has a wide range of applications in pesticide synthesis and drug synthesis. It can be used as a synthetic starting material for heterocyclic compounds, amide compounds, antibacterial drugs, etc.

Preparation Method:
Ethyl 3-oxo-4-phenoxybutyrate can be obtained by the esterification of phenol and ethyl 3-bromobutyrate under alkaline conditions. The reaction conditions generally require the addition of a base catalyst and are carried out at a suitable temperature.

Safety Information:
Ethyl 3-oxo-4-phenoxybutyrate has limited toxicity information, but as a chemical, attention should be paid to its safe operation. Avoid direct contact with skin, eyes and respiratory tract, and wear appropriate protective equipment, including chemical protective gloves and goggles. Pay attention to fire prevention and ventilation during operation. If inhaled or ingested by mistake, seek medical attention immediately. During storage and transportation, keep away from open flames and heat sources to ensure that the container is sealed.

It should be noted that this is only a general description of Ethyl 3-oxo-4-phenoxybutyrate. For specific safety information, please refer to the safety data sheet of the compound. In the laboratory use or industrial production process, please refer to the relevant safety operation guidelines and regulations for operation.

Last Update：2024-04-09 19:05:49